mAB List

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WorkFlow

Flow Chart

Description

- The Scan of Input amino-acid sequence(s) for monoclonal antibodies (mABs) will identify Domains, Complementary-Determining Regions and Disulfide bonds

- Implemented types of mABs can be found HERE

- The Search in PDB finds Homologous Structures for each mAB's domain

- Structural templates can be defined by selecting particular PDB structure for each domain separately

- The 3D arrangement of the domain is determined by spatial parameters for translation and rotation

- Model structure for each Template and Parameters Set Up can be finally Built